The Q2 2025 Spark100 continues—this time, we’re heading to the Northeast.
Known for its powerhouse tech hubs and storied startup roots, the Northeast region is home to some of the sharpest minds and most ambitious builders in the country. From edtech platforms reimagining student engagement to cybersecurity startups safeguarding the digital economy, these companies are tackling complex challenges head-on—and scaling fast.
Presented by DuploCloud and SaaS Brass, the Spark100 honors early-stage startups gaining serious momentum post-seed. These founders are reshaping industries, rewriting workflows, and laying the groundwork to become tomorrow’s category leaders.
This regional batch reflects what makes Northeast tech unique: a blend of grit, speed, and smart execution. Whether they’re disrupting healthcare, powering developer ecosystems, or transforming how we learn and work—these companies are showing what’s possible when innovation meets precision.
Meet the next 25 honorees—and stay tuned, because the journey isn’t over yet.
Learn more about the Spark100 and see the entire list of honorees at duplocloud.com/spark100.
Q2 2025 | Spark100 Honorees
Amperos Health
Amperos Health began its journey with a bold mission: revolutionizing healthcare through precision medicine. Facing the daunting challenge of transforming complex patient data into actionable insights, they navigated early hurdles by harnessing advanced analytics to personalize patient care. Each breakthrough deepened their commitment, as they evolved their approach to deliver more precise, impactful therapies. Their determination and innovative pivoting have enabled healthcare providers to make smarter decisions and significantly improve patient outcomes. Amperos Health stands out by bridging technology and compassion, illuminating the path toward a future where precision medicine is accessible and transformative for all.
Learn more at https://www.amperoshealth.com/
Lynx
Navigating the complex intersection of healthcare and finance has long been a significant challenge for businesses, leaving many struggling with fragmented financial services and inefficient payment processes. Founded with a clear vision for streamlined integration, Lynx delivers an elegant solution—a robust, API-driven platform that seamlessly unifies healthcare financial services, banking, investments, and payments. By empowering businesses to effortlessly embed comprehensive fintech solutions, Lynx enhances both operational efficiency and customer experience. This thoughtful innovation and early market impact underscore why Lynx is a deserving honoree in the Spark100.
Learn more at https://www.lynx-fh.com/
Doctronic
Amidst the complexities and uncertainties of healthcare diagnostics, Doctronic set forth on a quest to bridge the gap between artificial intelligence and human intuition. Recognizing the critical need for precise, timely diagnoses, they developed a revolutionary digital doctor powered by generative AI and machine learning. Collaborating seamlessly with human medical professionals, Doctronic overcame initial skepticism, continuously refining its technology to become an indispensable ally in patient care. With each diagnosis, the company’s breakthrough tech deepens trust and enhances medical accuracy, distinguishing Doctronic as a leading innovator in AI-driven healthcare, steadfastly committed to enhancing patient outcomes and redefining medical diagnostics.
Learn more at https://www.doctronic.ai/
FlexPoint
FlexPoint began its journey determined to solve the complexities of financial management that businesses face daily. Initially challenged by manual, error-prone invoicing processes, the company swiftly pivoted, harnessing automation to revolutionize billing efficiency. Breakthroughs like reducing receivable periods by 70% and achieving 99% automated invoicing allowed clients such as Loud & Clear and tekRESCUE to experience dramatic growth and streamlined operations. Client testimonials emphasize the profound impact of FlexPoint, noting staggering revenue growth and substantial operational savings. With an unwavering commitment to innovation and customer success, FlexPoint stands out as a dependable beacon guiding businesses through financial transformation.
Learn more at https://www.getflexpoint.com
Superblocks
Developers face increasing pressure to rapidly build intuitive, secure, and scalable applications—a challenge often hindered by repetitive coding and resource constraints. Superblocks, co-founded by visionary leaders who deeply understand developers’ pains, addresses this inefficiency by providing ready-made UI templates, AI-powered interfaces, and generative app-building services. Their unique platform accelerates frontend development by 10x, empowers junior engineers to perform senior-level tasks, and substantially reduces ticket resolution times. With clear customer wins and tangible efficiency gains already evident, Superblocks’ early momentum perfectly positions them among innovative industry leaders, earning them a prominent spot on the Spark100.
Learn more at https://www.superblocks.com
PhaseV
PhaseV embarked on a heroic quest to revolutionize clinical trials, facing the daunting challenge of inefficiencies and hidden insights. Armed with AI-driven tools and causal machine learning, they uncovered clinically meaningful patient subgroups previously unseen, transforming complex trials into streamlined successes. Notably, their site selection and indication sequencing modules became game-changers, optimizing recruitment and identifying promising new therapeutic pathways. Praised by industry leaders for delivering data-driven confidence and actionable insights, PhaseV stands apart as a beacon of innovation, significantly advancing the pharmaceutical landscape from their stronghold in Boston, Massachusetts.
Learn more at https://phasevtrials.com
dub
Dub began its quest to simplify investing, confronting the complexity and risks that deter many from the financial markets. Driven by the insight that investors sought trustworthy guidance, Dub pioneered a copy-trading platform, empowering users to mirror successful investment strategies effortlessly. The platform quickly resonated, bridging the gap between novice investors and seasoned market veterans. With a Series A funding fueling their momentum, Dub stands out by democratizing financial wisdom, making strategic investing accessible to everyone. Their journey marks a transformative shift in financial services, highlighting the power of shared knowledge and collaborative growth in the investing community.
Learn more at https://www.dubapp.com
AgentSmyth
Financial markets are inundated with data, overwhelming traders and analysts seeking actionable insights. Recognizing this challenge, AgentSmyth introduces specialized AI agents designed to simplify complex financial analysis, providing precise automated insights swiftly and accurately. Harnessing advanced artificial intelligence, founders of AgentSmyth have empowered users to make informed, confident decisions without the exhaustive manual research previously required. Their innovative blend of technology and financial expertise has quickly gained traction among financial professionals, positioning AgentSmyth as a pivotal player in streamlining trading processes. This impactful approach to financial analysis underscores why AgentSmyth is celebrated in this iteration of the Spark100.
Learn more at https://www.agentsmyth.com
OatFi
OatFi began its quest with a clear vision: addressing the complexities businesses faced in accessing working capital. Navigating the intricate landscape of B2B payments, the company quickly recognized an opportunity to empower platforms by embedding seamless financial tools. This pivot transformed their journey, crafting an infrastructure that revolutionizes how payment platforms offer working capital. Today, with strong momentum fueled by their Series A funding, OatFi stands distinctively in fintech, providing robust, turn-key solutions that not only streamline financial transactions but also unlock unprecedented growth opportunities for businesses across the financial ecosystem.
Learn more at http://www.oatfinancial.com
Rally UXR
User research teams often grapple with fragmented tools and cumbersome processes, slowing down valuable insights. Rally UXR tackles this head-on with a specialized CRM platform that seamlessly automates outreach, scheduling, incentives, and participant management. Teams at HelloFresh and Angi praise Rally for streamlining their operations, significantly reducing recruitment time and costs. “Rally has single-handedly taken our complicated recruitment approach and built out an engaging, time-saving process,” shared one senior researcher. With impressive early momentum and clear customer validation, Rally UXR is making user research simpler and more impactful, rightfully earning their spot in the Spark100.
Learn more at http://www.rallyuxr.com
Pickle
In a crowded fashion world, Pickle boldly stepped forth on a mission to solve a universal wardrobe dilemma—accessing trendy outfits without the expense or the clutter. Starting as a peer-to-peer clothing rental marketplace, Pickle transformed closets into a thriving community of shared fashion, allowing users to rent and lend clothing seamlessly. Influencers like Madi Kahn praised it as a wardrobe and wallet game-changer, while users discovered a profitable side hustle. Pickle’s breakthrough lay in empowering communities, turning fashion lovers into entrepreneurs and trendsetters, making it stand out by perfectly blending style, sustainability, and savings.
Learn more at https://www.shoponpickle.com
Glide
Community banks and credit unions have long struggled to keep pace with rapid digital transformation, often hindered by legacy technology and limited resources. Glide, founded with a clear vision to empower these critical community institutions, provides an innovative fintech platform tailored specifically to modernize and streamline their operations. By bridging the gap between traditional banking and cutting-edge technology, Glide enables local banks and credit unions to compete effectively in a digital-first world. Their early achievements in enhancing operational efficiencies have positioned Glide as a leader in fintech innovation, earning them a well-deserved spot in this iteration of the Spark100.
Learn more at https://withglide.com/
SplxAI
Conversational AI applications offer enormous potential but also introduce critical security vulnerabilities that traditional methods struggle to address. SplxAI, founded to solve this precise challenge, provides automated pentesting solutions specifically designed for securing generative and conversational AI technologies. By leveraging sophisticated SaaS tools, SplxAI ensures continuous and comprehensive protection, proactively identifying and mitigating risks in real time. Their unique approach streamlines security for businesses deploying AI, driving trust and reliability in AI-powered interactions. This thoughtful, forward-looking solution positions SplxAI as a key player in AI security and underscores why they’re honored in this iteration of the Spark100.
Learn more at https://splx.ai
VulnCheck
Organizations today grapple with increasingly sophisticated cyber threats, often lacking clear visibility into critical vulnerabilities. VulnCheck addresses this pressing challenge head-on, delivering advanced cyber threat intelligence powered by AI-driven analysis. By providing precise insights into exploits and vulnerabilities, VulnCheck empowers businesses to proactively protect their digital infrastructure, ensuring secure and continuous operational integrity. This impactful approach has quickly established VulnCheck as a vital partner in cybersecurity, reflecting their early momentum and commitment to innovation—earning their rightful recognition in this iteration of the Spark100.
Learn more at https://vulncheck.com
Acai Travel
Born from the complexity of travel operations, Acai Travel set out to conquer inefficiencies plaguing customer services in the bustling travel industry. Navigating early challenges, the team pivoted toward AI-driven automation, reshaping interactions and streamlining processes. Their breakthrough was evident with clients like World Travel, Inc., who reported a dramatic 19% reduction in average handling time, and Kiwi.com, which praised Acai’s effectiveness in policy management and error reduction. Now, distinguished by their smart technology and impactful customer experiences, Acai Travel continues to redefine the landscape, offering leaner, faster, and more efficient travel solutions.
Learn more at https://www.acaitravel.com/
Manifest
In a digital landscape riddled with vulnerabilities, Manifest embarked on a mission to protect the intricate pathways of software supply chains. Recognizing early that merely generating an SBOM wasn’t enough, they pivoted towards actionable cybersecurity strategies. “Manifest is doing something with it,” commended a Security Lead from a $50 billion digital payments giant, highlighting their proactive stance and tangible impact. With their groundbreaking approach, Manifest swiftly transformed into a trusted guardian in cybersecurity, setting itself apart by not just diagnosing, but fundamentally redefining how businesses navigate software security risks. Their journey exemplifies innovation, resilience, and profound industry impact.
Learn more at http://www.manifestcyber.com
Meadow
In the often-overwhelming sea of higher education finances, Meadow stepped forward on a hero’s journey to simplify and enhance student payment experiences. Facing the daunting challenge of financial friction that prevents many students from pursuing their education, Meadow evolved into a powerful engagement and billing platform. Their breakthrough transformed campus financial services, with student receivables hitting historic lows and administrative burdens lifting dramatically—”It feels like we have a bigger office,” remarked one relieved director. Today, Meadow stands out as the lifeline institutions trust, ensuring more students can confidently embark upon their educational journeys.
Learn more at https://www.meadowfi.com
Salvo Health
Salvo Health embarked on a courageous journey to ease the burden of chronic gut conditions, recognizing the isolation and struggle experienced by countless patients. As an app-based specialty care provider, they navigated early challenges and swiftly pivoted towards a patient-centric digital experience, revolutionizing gut health management. Their breakthrough came with astonishing results—76% of patients reported improvement within just four weeks, while 84% praised their experience as superior healthcare. Standing apart in healthcare innovation, Salvo Health’s compassionate approach and technological prowess continue to transform lives, offering relief and hope to those battling chronic conditions.
Learn more at https://www.salvohealth.com/
1Fort
Businesses navigating the complexities of cyber insurance often face overwhelming security requirements, causing confusion and delays. Co-founded by dedicated innovators, 1Fort leverages cutting-edge AI and SaaS solutions to streamline cyber insurance processes, pre-fill forms, and identify security gaps seamlessly. Renowned businesses like CEC Facilities Group and FanDuel have witnessed firsthand the platform’s effectiveness, significantly reducing renewal times and strengthening cyber resilience. With its empathetic approach and tangible, real-world results, 1Fort’s impactful early traction underscores why they’re being celebrated in the Spark100 for redefining the intersection of insurance and security technology.
Learn more at https://www.1fort.com
Brellium
Healthcare providers face tremendous pressure ensuring clinical documentation meets ever-changing billing and compliance standards, often risking costly errors and inefficiencies. Brellium, founded by innovators committed to easing these complexities, introduces an AI-powered clinical note auditor designed to streamline audits and uphold customized clinical standards effortlessly. Their SaaS solution meticulously aligns documentation with billing protocols, significantly diminishing audit times and potential compliance issues. Brellium’s intuitive approach to a previously cumbersome process exemplifies tangible innovation in healthcare administration, earning their well-deserved recognition in the Spark100 spotlight.
Learn more at https://www.brellium.com/
Sohar Health
In the intricate landscape of behavioral health care, Sohar Health embarked on a mission to alleviate the burdensome complexities of insurance verification. Early hurdles revealed profound insights: manual processes were not just inefficient but risked patient stability. Leveraging AI-driven solutions and robust EHR integration, Sohar pioneered real-time eligibility updates, transforming hours-long tasks into mere seconds. This breakthrough empowered providers like Talkiatry, significantly boosting patient conversions and operational efficiency—a remarkable 8:1 ROI within a year. With precise, dependable technology, Sohar Health uniquely stands out, reshaping patient intake workflows and setting new standards for accuracy and care in healthcare management.
Learn more at https://www.soharhealth.com
Trayd
In the bustling construction landscape, payroll and people management once stood as towering hurdles, tangled in manual tracking and disconnected data. Trayd emerged amidst this chaos, determined to simplify construction payroll complexities. Through focused innovation, their platform integrated time-tracking, payroll automation, and meticulous people management into one seamless solution. Praised by industry leaders like Julian Perez for its unique, tailored insights and Nick Singh for transforming operational efficiency, Trayd has swiftly become indispensable. Their breakthrough lies not just in technology, but in empowering construction businesses to navigate payroll effortlessly, distinguishing them clearly as a visionary force within their industry.
Learn more at https://www.buildtrayd.com/
Ribbon
Ribbon’s journey began in the bustling heart of Toronto, where navigating the complex world of job searches felt overwhelming. Driven by the challenge job seekers faced, Ribbon pioneered an AI-powered platform to simplify and accelerate the job-hunting process. Their innovative breakthroughs, such as Resume+ and Jobs Copilot, offered users unprecedented insights, transforming resumes and streamlining applications. Testimonials from students and professionals alike echoed Ribbon’s impact: it turned rejections into interviews and stress into success. Standing out by empowering careers with precision and convenience, Ribbon continues to redefine how job seekers discover their dream jobs faster and smarter.
Learn more at https://www.ribbon.ai/
GoAudience
Businesses often struggle with identifying and reaching their ideal customers efficiently, wasting precious resources on broad, ineffective marketing strategies. Recognizing this pain point, GoAudience, founded by visionaries committed to smarter growth, leverages powerful AI technology and credit card spending data from 220 million US consumers to precisely pinpoint and engage high-intent audiences. Clients like Peluva and JustUs Skincare have significantly enhanced their market responsiveness and customer acquisition efficiency. Their clear success in streamlining customer targeting and boosting conversions underscores GoAudience’s innovative approach, earning them a well-deserved recognition in the Spark100.
Learn more at http://www.goaudience.com
Henry
In the bustling landscape of commercial real estate, brokers navigated a sea of paperwork and fragmented data, struggling to swiftly generate compelling deal presentations. Enter Henry, the generative AI copilot determined to streamline this daunting task. Faced initially with skepticism about AI’s role in real estate, Henry quickly proved itself invaluable by seamlessly integrating internal and external data sources. Brokers discovered newfound agility, crafting insightful deal decks within moments rather than days. Henry’s transformative breakthrough lies in simplifying complexity, making sophisticated data instantly accessible, and fundamentally reshaping how brokers operate—distinguishing itself clearly within the competitive SaaS and generative AI arenas.
Learn more at https://www.henry.ai/
Disclaimer:
The Spark100 recognition program is proudly sponsored by DuploCloud and SaaS Brass. As corporate sponsors, our goal is to celebrate and spotlight the achievements of innovative SaaS startups and their contributions to the tech ecosystem. While the Spark100 is an initiative of DuploCloud and SaaS Brass, the companies selected for recognition were chosen solely based on their recent funding milestones and industry impact.
About DuploCloud
DuploCloud is a no-code/low-code DevOps automation platform that empowers SaaS startups to scale faster by simplifying cloud infrastructure management. With an all-in-one solution for security, compliance, and deployment, DuploCloud enables teams to focus on building amazing software while we handle the heavy lifting of DevOps.
About SaaS Brass
SaaS Brass is a thriving community dedicated to connecting and supporting SaaS startup technical leaders. Through engaging events, knowledge sharing, and networking opportunities, we bring together the brightest minds in SaaS to collaborate, innovate, and grow.